弊社「修飾オリゴ合成サービス」に記載されていない修飾に関しては、Eurogentec社(ベルギー)の多彩な修飾サービスをご利用ください。
Eurogentec社で合成可能な修飾オリゴ
| Terminus and internal modification |
| 5'- PO4 |
3'- PO4 |
3' NH2-C6 |
| dR-NH2 |
Internal C6-NH2 dT |
Amino Propargyl dU |
| Amino Propargylcaproyl dU |
Amino dU |
3'- SH-C3 |
| Spacer C3 |
Spacer C8 (Octanediol) |
Spacer C9 |
| Spacer C18 |
HEG |
dSpacer C3 (Abasic site) |
| 3' Spacer C3 |
Alkaline phosphatase |
HRP |
| BSA |
5' Acrylamide (Acrydite®) |
3' glyceryl |
| 5'- TEG Cholesteryl |
3'- TEG Cholesteryl |
dR-Cholesteryl |
| 5'-MeO-Cl-Acridine |
3'-MeO-Cl-Acridine |
MeO-Cl-Acridine (int. labeling) |
| 5'-C2 Psoralen |
5'-C6 Psoralen |
3' Oligo-affinity support (PS) |
| 3' Oligo-affinity support (CPG) |
Carboxy dT |
3'-dC blocked |
| 2', 3'-ddC Blocked |
5'-SH-C6 |
|
| Non radioactive labeling |
| 5'-Biotin-TEG |
3'-Biotin-TEG |
dR-Biotin |
| Biotin-dT (1-3 int. labels/oligo) |
5'-Digoxigenin |
3'-Digoxigenin |
| Digoxigenin (1-3 labels/oligo) |
dR-Digoxigenin |
5'-TEG-Dinitrophenol |
| dR-Dinitrophenol |
Dinitrophenol (1-3 labels/oligo |
|
| Bases with altered pairing properties |
| Oligo spiking |
5-NitroIndole (Universal bases) |
3-Nitropyrrole |
| dP-(pyrimidine analogue) |
dK (purine analogue) |
dUracil |
| 3' dUracil |
5- Br-dU |
3' 5-Br-dU |
| 5-Br-dC |
8-Br-dA |
8-Br-dG |
| 6-dihydro-dU |
7-deaza-dA/dG |
8-Oxo-dG |
| 8-Oxo-dA |
6-Me-dG |
|
| Fluorescent Dyes |
| 5'-Cy®3 |
3'- Cy®3 |
Cy®3 internal |
| 5'- Cy®3.5 |
3'- Cy®3.5 |
Cy®3.5 internal |
| 5'- Cy®5 |
3'- Cy®5 |
Cy®5 internal |
| 5'- Cy®5.5 |
3'- Cy®5.5 |
Cy®5.5 internal |
| 3'-FAM |
dR-FAM |
FAM (1-3 labels/oligo) |
| 5'-Fluorescein |
3'-Fluorescein |
Fluorescein (1-3 labels/oligo) |
| 5'-HEX |
dR-HEX |
HEX-dT |
| 5'-TET |
dR-TET |
TET-dT |
| 5'-Texas Red® |
3'-Texas Red® |
Texas Red®(1-3 labels/oligo) |
| dR-Texas Red® |
Texas Red®dT |
5'-TAMRA |
| 3'-TAMRA |
dT-TAMRA |
5'-R6G |
| 3'-R6G |
dR-R6G |
R6G-dT |
| 5'-ROX |
dR-ROX |
ROX-dT |
| 5'-JOE |
3'-JOE |
dR-JOE |
| JOE-dT |
5'-Yakima yellow® |
5'-Bodipy®FL |
| 5'-Bodipy®530/550 |
5'-Bodipy®TR |
5'-Bodipy®TMR |
| 5' Alexa®350 |
5' Alexa®430 |
5' Alexa®488 |
| 5' Alexa®532 |
5' Alexa®546 |
5' Alexa®555 |
| 5' Alexa®568 |
5' Alexa®594 |
5' Alexa®633 |
| 5' Alexa®660 |
5' Alexa®667 |
5' Alexa®680 |
| 5' Alexa®700 |
5' Alexa®750 |
5' Cascade Blue® |
| 5' Marina Blue® |
5' Pacific Blue® |
|
| Quenchers |
| 3' DABCYL |
DABCYL-dT |
3' Eclipse® Dark Quencher |
| 5' Deep Dark Quencher I |
3' Deep Dark Quencher I |
dR-Deep Dark Quecher I |
| 3' Deep Dark Quencher II |
|
|
| LNA |
| Double Dye Oligonucleotides |
| 5' FAM+3' Eclipse®Dark Quencher or DDQI *5'FAM+3'TAMRA, 3' Eclipse® Dark Quencherは日本で合成 |
| 5' HEX+3' TAMRA, Eclipse®Dark Quencher or DDQI |
| 5' TET+3' TAMRA, Eclipse®Dark Quencher or DDQI |
| 5' Rhod/Rhod6G/ROX + 3' TAMRA, DDQI or DDQII |
| 5' TAMRA+3' DDQI or DDQII |
| 5' Texas Red®3'-DDQI or DDQII |
| 5' JOE+3' TAMRA, DDQI or DDQII |
| 5' Cy®5dyes+3' DDQII |
| 5' Yakima Yellow®+3' Eclipse®DDQ or DDQI |
| LNA Double-Dye Oligonucleorides |
| 5' FAM+3' TAMRA or DABCYL or Eclipse®Dark Quencher |
| 5' Yakima Yellow®3' DABCYL/Eclipse®Dark Quencher |
| Molecular Beacon |
| 5' FAM+3' DABCYL |
5' HEX+3' DABCYL |
5' TET+3' DABCYL |
| 5' Rhod/Rhod6G/ROX |
5' TAMRA +3' DABCYL |
5' Cascade Blue + 3' DABCYL |
| 5' BODIPY®Dyes + 3' DABCYL |
5' Alexa®Dyes + 3' DABCYL |
5' Cy®Dyes + 3' DABCYL |
| 5' JOE + 3' DABCYL |
5' Yakima Yellow® +3' DABCYL |
5' FAM+3' DABCYL (2' O-Me RNA) |
| 5' HEX/TET+3' DABCYL (2' O-Me RNA) |
|
|
| Scorpions® |
| Scorpions®primers |
| ROX/FAM FRET Scorpions®primers |
| Duplex Scorpions®probes |
| FRET Probes |
| 3' FAM FRET probe |
5' ROX FRET probe |
5' Cy® FRET probe |
| RNA |
| siRNA |
| Modified siRNA 5' HEX |
Modified siRNA 5' TET |
Modified siRNA 5' Fluorescein |
| Modified siRNA 5' 6-FAM |
Modified siRNA Internal Fluorecein |
Modified siRNA 5' TAMRA |
| Modified siRNA 5' Rhodamin |
Modified siRNA 5' Phosphate |
Modified siRNA 5' Alexa Fluor® |
| Antisense oligos |
| Phsphorothioate |
5' Iodo + 3' Phosphorothioates |
Methylphosphonate |
| RNA 2'-OMe |
RNA 2'-OMe Inosine |
RNA 2'-OMe-5-Me-C |
| RNA 2'-OMe propynyl-C |
RNA 2'-OMe propynyl-U |
C5-propyne dC |
| C5-propyne dU |
5-Me dC |
3' 5-Me dC |
